As the largest organ of the human body, the skin has a surface area of 1.8 m2, and its main function is to act as a physical barrier to protect the body from foreign organisms or toxic substances. Meanwhile, the skin is also where the body comes into contact with the external environment, so there are various types of microbes that are resident here. Skin microecology refers to an ecosystem composed of bacteria, fungi, viruses, mites and other microbes together with skin surface tissues, cells, various secretions, and microenvironment.
The interaction of skin microbes, hosts and external environment constitutes the skin microecological balance, forming the first biological barrier on the skin surface. Once this balance is broken, it may cause skin diseases or infections. Changes in skin microecology are related to the occurrence and development of various inflammatory and infectious diseases such as psoriasis, atopic dermatitis, acne and chronic wounds. Common skin surface flora includes Propionibacterium, Corynebacterium, Staphylococcus aureus, etc.
The main research directions of skin microbes including,
The specific service content includes the following aspects, microbial isolation & cultivation, microbial identification, microbial sequencing, microbial proteomics, microbial metabonomics, microbial genome editing and bioinformatics analysis.
OTU clustering | Taxonomic analysis | Phylogenetic analysis | Analysis based on OUT | Gene function analysis |
OTU distribution Rarefaction curve Shannon index curve Rank abundance curve Diversity index |
Community composition analysis Community correlation analysis Community difference analysis
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UniFrac analysis PCoA Phylogenetic tree |
OTU correlation analysis
RDA/CCA |
KEGG analysis GO analysis MetaCyc analysis EggNOG analysis CAZy analysis CARD analysis |
Skin health should not be neglected. If the skin microecological balance is broken, it may destroy the skin barrier and lead to the adverse development of the immune system, thus causing skin and even systemic diseases. Creative Biogene provides a complete solution for your skin microecology research, and invites you to enjoy a one-step service experience. It is sincerely looking forward to cooperating with you.
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